Evaluating pharmacokinetics of bempedoic acid in the treatment of hypercholesterolemia
Author:
Affiliation:
1. IRCCS AOU S. Orsola-Malpighi, Hypertension and Cardiovascular Risk Factors Research Center (DIMEC), University of Bologna, Bologna, Italy
2. Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy
Publisher
Informa UK Limited
Subject
Pharmacology,Toxicology,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/17425255.2021.1951222
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1. Heart Disease and Stroke Statistics—2015 Update
2. Safety and tolerability of injectable lipid-lowering drugs: an update of clinical data
3. ETC-1002 (Bempedoic acid) for the management of hyperlipidemia: from preclinical studies to phase 3 trials
4. The effect of (−)-hydroxycitrate on the activity of the low-density-lipoprotein receptor and 3-hydroxy-3-methylglutaryl-CoA reductase levels in the human hepatoma cell line Hep G2
5. Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis
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