Evolving approaches on measurements and applications of intracellular free drug concentration and Kpuu in drug discovery
Author:
Affiliation:
1. Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Groton, CT, USA
2. Pharmacokinetics, Dynamics and Metabolism, Pfizer Worldwide Research and Development, Cambridge, MA
Publisher
Informa UK Limited
Subject
Pharmacology,Toxicology,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/17425255.2021.1935866
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1. The effect of plasma protein binding on in vivo efficacy: misconceptions in drug discovery
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