Breaking barriers: the latest insights into KRAS G12C inhibitors
Author:
Affiliation:
1. Faculty of Medicine, Saint Joseph University of Beirut, Beirut, 11072180, Lebanon
2. Department of Hematology-Oncology, Faculty of Medicine, Saint Joseph University of Beirut, Beirut, 11072180, Lebanon
Publisher
Informa UK Limited
Link
https://www.tandfonline.com/doi/pdf/10.1080/14796694.2024.2394009
Reference19 articles.
1. KRAS mutation: from undruggable to druggable in cancer
2. K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions
3. From bench to bedside: current development and emerging trend of KRAS-targeted therapy
4. KRYSTAL-12: Phase 3 study of adagrasib versus docetaxel in patients with previously treated advanced/metastatic non-small cell lung cancer (NSCLC) harboring a KRASG12C mutation.
5. Sotorasib plus carboplatin and pemetrexed in KRAS G12C advanced NSCLC: Updated analysis from the international CodeBreaK 101 trial.
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