A plain language summary of the results from the phase 2b HERIZON-BTC-01 study of zanidatamab in participants with HER2-amplified biliary tract cancer

Author:

Harding James J1,Fan Jia2,Oh Do-Youn3,Choi Hye Jin4,Kim Jin Won5,Chang Heung-Moon6,Bao Lequn7,Sun Hui-Chuan2,Macarulla Teresa8,Xie Feng9,Metges Jean-Phillippe10,Ying Jie'er11,Bridgewater John12,Lee Myung-Ah13,Tejani Mohamedtaki A14,Chen Emerson Y15,Kim Dong Uk16,Wasan Harpreet17,Ducreux Michel18,Bao Yuanyuan19,Lindsey Stacie20,Bachini Melinda20,Morement Helen21,Boyken Lisa22,Ma Jiafang19,Garfin Phillip23,Pant Shubham24,

Affiliation:

1. Memorial Sloan Kettering Cancer Center, New York, NY, USA

2. Zhongshan Hospital of Fudan University, Shanghai, China

3. Seoul National University Hospital, Cancer Research Institute, Seoul National University College of Medicine, Integrated Major in Innovative Medical Science, Seoul National University Graduate School, Seoul, South Korea

4. Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, South Korea

5. Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, South Korea

6. Asan Medical Center, University of Ulsan College of Medicine, Seoul, South Korea

7. Hubei Cancer Hospital, Wuhan, Hubei, China

8. Vall d´Hebrón University Hospital, Vall d´Hebrón Institute of Oncology (VHIO), Barcelona, Spain

9. The Third Affiliated Hospital of the Chinese people's Liberation army Naval Military Medical University, Shanghai, China

10. CHRU de Brest – Hopital Morvan, ARPEGO Network, Brest, France

11. Zhejiang Cancer Hospital, Hangzhou, Zhejiang, China

12. University College London Cancer Institute, London, UK

13. The Catholic University of Korea, Seoul St Mary's Hospital, Seoul, South Korea

14. AdventHealth, Altamonte Springs, FL, USA

15. Oregon Health & Science University, Portland, OR, USA

16. Biomedical Research Institute, Pusan National University Hospital, Busan, South Korea

17. Hammersmith Hospital, Imperial College London, London, UK

18. Université Paris-Saclay, Gustave Roussy, Villejuif, France

19. BeiGene, Beijing, China

20. Cholangiocarcinoma Foundation, UT, USA

21. AMMF – The Cholangiocarcinoma Charity, Stansted, UK

22. Zymeworks Inc., Vancouver, BC, Canada

23. Jazz Pharmaceuticals, Palo Alto, CA, USA

24. MD Anderson Cancer Center, Houston, TX, USA

Publisher

Informa UK Limited

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