A study protocol for an ongoing multi-arm, randomized, double-blind, sham-controlled clinical trial with digital features, using portable transcranial electrical stimulation and internet-based behavioral therapy for major depression disorders: The PSYLECT study

Author:

Borrione Lucas12ORCID,Cirillo Patricia C12,Aparicio Luana VM12ORCID,Cavendish Beatriz A12,Valiengo Leandro12,Moura Darin O12,de Souza Juliana P12,Luethi Matthias S12,Klein Izio12ORCID,Bariani Bruna12,Gallucci-Neto José12,Suen Paulo12ORCID,Padberg Frank3,Goerigk Stephan3,Vanderhasselt Marie-Anne456,De Deng Zhi78,O’Shea Jacinta9,Lotufo Paulo A10,Bensenor Isabela M10,Brunoni Andre R1210ORCID

Affiliation:

1. Service of Interdisciplinary Neuromodulation, Department and Institute of Psychiatry, University of São Paulo Medical School, São Paulo, Brazil

2. Laboratory of Neuroscience and National Institute of Biomarkers in Psychiatry, Department and Institute of Psychiatry, University of São Paulo Medical School, São Paulo, Brazil

3. Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Munich, Germany

4. Department of Head and Skin, Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium

5. Ghent Experimental Psychiatry (GHEP) lab, Ghent University, Ghent, Belgium

6. Department of Experimental Clinical and Health Psychology, Psychopathology and Affective Neuroscience Lab, Ghent University, Ghent, Belgium

7. Noninvasive Neuromodulation Unit, Experimental Therapeutic & Pathophysiology Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, MD, USA

8. Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, North Carolina, USA

9. Wellcome Centre for Integrative Neuroimaging, Oxford Centre for Human Brain Activity, Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK

10. Center for Clinical and Epidemiological Research & Interdisciplinary Center for Applied Neuromodulation, University Hospital, University of São Paulo, São Paulo, Brazil

Funder

the public governmental agency FAPESP

Publisher

Informa UK Limited

Subject

Pharmacology (medical),Neurology (clinical),General Neuroscience

Reference63 articles.

1. Collaborators GBD. National incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990-2017: a systematic analysis. 2018

2. [cited 2021 Dec 1]. Available from: https://leicester.figshare.com/articles/journal_contribution/Global_regional_and_national_incidence_prevalence_and_years_lived_with_disability_for_354_diseases_and_injuries_for_195_countries_and_territories_1990-2017_a_systematic_analysis_for_the_Global_Burden_of_Disease_Study_2017_/10200149/files/18383459.pdf

3. Acute and Longer-Term Outcomes in Depressed Outpatients Requiring One or Several Treatment Steps: A STAR*D Report

4. Evidence-based guidelines for treating depressive disorders with antidepressants: A revision of the 2000 British Association for Psychopharmacology guidelines

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