1. The SmartState Center for Medication Safety and Efficacy and the Department of Family Medicine, the University of South Carolina, Columbia, South Carolina, (CLB, PG, KK, CN, WJH), the City of Hope National Cancer Institute Designated Comprehensive Cancer Center, Duarte, California (CLB, SJR), Imperial College London (RPG), the University of Nebraska College of Medicine/Omaha Omaha, Nebraska (JOA), Duarte, California (CLB)