Investigation of mixing homogeneity of binary particle systems in high-shear wet granulator by DEM-Reference-Cited by-同舟云学术

Investigation of mixing homogeneity of binary particle systems in high-shear wet granulator by DEM

Published:2023-02-01 Issue:2 Volume:49 Page:179-188
ISSN:0363-9045
Container-title:Drug Development and Industrial Pharmacy
language:en
Short-container-title:Drug Development and Industrial Pharmacy

Author:

Fan Renyu¹,Zhao Mengtao¹,Luo Linxiu¹,Wang Yuting¹,Zhou Kangming¹,Liu Zeng¹,Zhou Yu¹,Guan Tianbing¹,Sun Huimin²,Dai Chuanyun¹

Affiliation:

1. Chongqing Key Laboratory of Industrial Fermentation Microorganisms, College of Chemistry and Chemical Engineering, Chongqing University of Science and Technology, Chongqing, China

2. NMPA Key Laboratory for Quality Research and Evaluation of Pharmaceutical Excipients, National Institutes for Food and Drug Control, Beijing, China

Funder

National Science and Technology Major New Drug Creation Special Project

Chongqing Technology Innovation and Application Development Special Project

Publisher

Informa UK Limited

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology

Link

https://www.tandfonline.com/doi/pdf/10.1080/03639045.2023.2194993

Reference52 articles.

1. Recent trends and future perspective of pharmaceutical wet granulation for better process understanding and product development

2. A comprehensive review on process and engineering aspects of pharmaceutical wet granulation

3. A review of high shear wet granulation for better process understanding, control and product development

4. Analysis of the origins of content non-uniformity in high-shear wet granulation

5. Effect of operating conditions and physico–chemical properties on the wet granulation kinetics in high shear mixer