Mechanism of enhanced oral absorption of akebia saponin D by a self-nanoemulsifying drug delivery system loaded with phospholipid complex

Author:

Wang Yuhui1,Shen Jinyang2,Yang Xiaolin34,Jin Ye5,Yang Zhonglin6,Wang Rufeng47,Zhang Fuming4,Linhardt Robert J.489

Affiliation:

1. Department of Pharmacology, Guilin Medical University, Guilin, China;

2. Institute of Traditional Chinese Veterinary Medicine, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China;

3. Jiangsu Key Laboratory of Research and Development in Marine Bio-resource Pharmaceutics, Nanjing University of Chinese Medicine, Nanjing, China;

4. Department of Chemical and Biological Engineering, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY, USA;

5. Pharmacy Department, Yangzhou Hospital of Traditional Chinese Medicine, Yangzhou, China;

6. State Key laboratory of natural Medicines, China Pharmaceutical University, Nanjing, China;

7. Chinese Medicines and the SATCM Key Laboratory for New Resources and Quality Evaluation of Chinese Medicines, Institute of Chinese Material Medica, Shanghai University of Traditional Chinese Medicine, Shanghai, China;

8. Department of Chemistry, Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY, USA;

9. Departments of Biology, Biomedical Engineering, Center for Biotechnology and Interdisciplinary Studies Rensselaer Polytechnic Institute, Troy, NY, USA

Funder

National Natural Science foundation of China

administration of Traditional Chinese Medicine of Jiangsu Province

special funding for

Guangxi BaGui Scholars

Publisher

Informa UK Limited

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology

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