Effects of crystalline state and self-nanoemulsifying drug delivery system (SNEDDS) on oral bioavailability of the novel anti-HIV compound 6-benzyl-1-benzyloxymethyl-5-iodouracil in rats-Reference-Cited by-同舟云学术

Effects of crystalline state and self-nanoemulsifying drug delivery system (SNEDDS) on oral bioavailability of the novel anti-HIV compound 6-benzyl-1-benzyloxymethyl-5-iodouracil in rats

Published:2017-11-08 Issue:2 Volume:44 Page:329-337
ISSN:0363-9045
Container-title:Drug Development and Industrial Pharmacy
language:en
Short-container-title:Drug Development and Industrial Pharmacy

Author:

Lu Ying-Yuan¹,Dai Wen-Bing²,Wang Xin¹,Wang Xiao-Wei³,Liu Jun-Yi³,Li Pu¹,Lou Ya-Qing¹,Lu Chuang⁴,Zhang Qiang²,Zhang Guo-Liang¹

Affiliation:

1. Department of Pharmacology, School of Basic Medical Science, Beijing (Peking) University, Beijing, PR China;

2. State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Beijing (Peking) University, Beijing, PR China;

3. Department of Chemical Biology, School of Pharmaceutical Sciences, Beijing (Peking) University, Beijing, PR China;

4. Department of Drug Metabolism & Pharmacokinetics (DMPK), Biogen, Cambridge, MA, USA

Funder

National Natural Science foundation of China

National Basic Research Program of China

Publisher

Informa UK Limited

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology

Link

https://www.tandfonline.com/doi/pdf/10.1080/03639045.2017.1391837

Reference48 articles.

1. Improving bioavailability and biodistribution of anti-HIV chemotherapy

2. The Challenge of Viral Reservoirs in HIV-1 Infection

3. The Dual Role of Pharmacogenetics in HIV Treatment: Mutations and Polymorphisms Regulating Antiretroviral Drug Resistance and Disposition

4. Safety Assessment, In Vitro and In Vivo, and Pharmacokinetics of Emivirine, a Potent and Selective Nonnucleoside Reverse Transcriptase Inhibitor of Human Immunodeficiency Virus Type 1

5. Non-nucleoside reverse transcriptase inhibitors: a review on pharmacokinetics, pharmacodynamics, safety and tolerability

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