Feasibility of Direct Vitrectomy-Sparing Subretinal Injection for Gene Delivery in Large Animals

Author:

Stranak Zbynek1,Ardan Taras2,Nemesh Yaroslav2,Toms Maria34,Toualbi Lyes34,Harbottle Richard5,Ellederova Zdenka2,Lytvynchuk Lyubomyr67,Petrovski Goran8910,Motlik Jan2,Moosajee Mariya3411,Kozak Igor12

Affiliation:

1. Department of Ophthalmology, Charles University, Prague and the Kralovske Vinohrady University Hospital, Prague, Czech Republic

2. Libechov Institute of Animal Physiology and Genetics, Czech Academy of Sciences, Libechov, Czech Republic

3. UCL Institute of Ophthalmology, London, United Kingdom

4. The Francis Crick Institute, London, United Kingdom

5. German Cancer Research Center (DKFZ), Heidelberg, Germany

6. Department of Ophthalmology, Justus-Liebig-University Giessen, Eye Clinic, University Hospital Giessen and Marburg GmbH, Giessen, Germany

7. Karl Landsteiner Institute for Retinal Research and Imaging, Vienna, Austria

8. Department of Ophthalmology, Oslo University Hospital, Kirkeveien 166, Oslo, Norway

9. Center for Eye Research and Innovative Diagnostics, Department of Ophthalmology, Oslo University Hospital and Institute for Clinical Medicine, University of Oslo, Oslo, Norway

10. Department of Ophthalmology, University of Split School of Medicine and University Hospital Centre, Split, Croatia

11. Moorfields Eye Hospital NHS Foundation Trust, London, United Kingdom

12. Department of Vitreoretinal Surgery and Research and Innovation, Moorfields Eye Hospitals UAE, Abu Dhabi

Funder

Johannes Amos Comenius Programme (Research Excellence in Regenerative medicine

AV21 Strategy (Czech Academy of Sciences) and IAPG institutional support

Moorfields Eye Charity

Publisher

Informa UK Limited

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