Therapeutic Effects of Idebenone on Leber Hereditary Optic Neuropathy
Author:
Affiliation:
1. State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University , Guangzhou, P.R. China
Funder
National Natural Science Foundation of China
Natural Science Foundation of Guangdong province of China
Publisher
Informa UK Limited
Subject
Cellular and Molecular Neuroscience,Sensory Systems,Ophthalmology
Link
https://www.tandfonline.com/doi/pdf/10.1080/02713683.2020.1736307
Reference28 articles.
1. Mitochondrial Optic Neuropathies: How Two Genomes may Kill the Same Cell Type?
2. Inherited mitochondrial optic neuropathies
3. Quality of Life in Patients with Leber Hereditary Optic Neuropathy
4. Nuclear expression of mitochondrial ND4 leads to the protein assembling in complex I and prevents optic atrophy and visual loss
5. Idebenone for Leber's hereditary optic neuropathy
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1. Genetic variants affecting NQO1 protein levels impact the efficacy of idebenone treatment in Leber hereditary optic neuropathy;Cell Reports Medicine;2024-02
2. Case report: Mutations in DNAJC30 causing autosomal recessive Leber hereditary optic neuropathy are common amongst Eastern European individuals;Frontiers in Neurology;2023-12-01
3. Apparent Opportunities and Hidden Pitfalls: The Conflicting Results of Restoring NRF2-Regulated Redox Metabolism in Friedreich’s Ataxia Pre-Clinical Models and Clinical Trials;Biomedicines;2023-04-27
4. Mitochondrial dysfunction in cognitive neurodevelopmental disorders: Cause or effect?;Mitochondrion;2023-03
5. Leber’s Hereditary Optic Neuropathy with Mitochondrial DNA Mutation G11778A: A Systematic Literature Review and Meta-Analysis;BioMed Research International;2023-01-24
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