TGFβ2 Regulates Human Trabecular Meshwork Cell Contractility<i>via</i>ERK and ROCK Pathways with Distinct Signaling Crosstalk Dependent on the Culture Substrate-Reference-Cited by-同舟云学术

TGFβ2 Regulates Human Trabecular Meshwork Cell ContractilityviaERK and ROCK Pathways with Distinct Signaling Crosstalk Dependent on the Culture Substrate

Published:2022-05-19 Issue:8 Volume:47 Page:1165-1178
ISSN:0271-3683
Container-title:Current Eye Research
language:en
Short-container-title:Current Eye Research

Author:

Li Haiyan¹²,Henty-Ridilla Jessica L.³⁴,Bernstein Audrey M.¹²³⁵,Ganapathy Preethi S.¹⁴,Herberg Samuel¹²³⁶⁷^ORCID

Affiliation:

1. Department of Ophthalmology and Visual Sciences, SUNY Upstate Medical University, Syracuse, NY, USA

2. Department of Cell and Developmental Biology, SUNY Upstate Medical University, Syracuse, NY, USA

3. Department of Biochemistry and Molecular Biology, SUNY Upstate Medical University, Syracuse, NY, USA

4. Department of Neuroscience and Physiology, SUNY Upstate Medical University, Syracuse, NY, USA

5. Syracuse VA Medical Center, New York VA Health Care, Syracuse, NY, USA

6. BioInspired Institute, Syracuse University, Syracuse, NY, USA

7. Department of Biomedical and Chemical Engineering, Syracuse University, Syracuse, NY, USA

Funder

National Institutes of Health

Merit Review Award

United States Department of Veteran’s Affairs

American Glaucoma Society

Syracuse University BioInspired Pilot Grant

SUNY Upstate Medical University Department of Ophthalmology

Visual Sciences from Research to Prevent Blindness

Lions Region 20-Y1

RPB Career Development Awards

Harper-Inglis Memorial for Eye Research

The Peierls Foundation

That Man May See, and Research to Prevent Blindness.

Publisher

Informa UK Limited

Subject

Cellular and Molecular Neuroscience,Sensory Systems,Ophthalmology

Link

https://www.tandfonline.com/doi/pdf/10.1080/02713683.2022.2071943

Reference74 articles.

1. Modulation of extracellular matrix turnover in the trabecular meshwork

2. Open-Angle Glaucoma

3. Aqueous humor contains transforming growth factor-beta and a small (less than 3500 daltons) inhibitor of thymocyte proliferation.

4. Transforming growth factor-β2 levels in aqueous humor of glaucomatous eyes

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