The role of QRS complex prolongation in predicting severe toxicity in single-xenobiotic overdose

Author:

Simon Mark12ORCID,Kaplan Sabrina12,Muschler Karen1,Hoyte Christopher13,Brent Jeffrey3ORCID

Affiliation:

1. Rocky Mountain Poison and Drug Safety, Denver Health and Hospital Authority, Denver, CO, USA

2. Department of Emergency Medicine, Denver Health and Hospital Authority, Denver, CO, USA

3. Department of Emergency Medicine, University of CO, Aurora, CO, USA

Publisher

Informa UK Limited

Reference32 articles.

1. The effect of toxic and therapeutic doses of tricyclic antidepressant drugs on intracardiac conduction;Vohra J;Eur J Cardiol,1975

2. Effects of imipramine on cellular electrophysiological properties of cardiac purkinje fibers;Rawling DA;J Pharmacol Exp Ther,1979

3. Treatment of ventricular tachyarrhythmias resulting from amitriptyline toxicity in dogs;Nattel S;J Pharmacol Exp Ther,1984

4. Mechanism of reversal of toxic effects of amitriptyline on cardiac purkinje fibers by sodium bicarbonate;Sasyniuk BI;J Pharmacol Exp Ther,1984

5. Value of the QRS Duration versus the Serum Drug Level in Predicting Seizures and Ventricular Arrhythmias after an Acute Overdose of Tricyclic Antidepressants

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