Characterization and initial demonstration of <i>in vivo</i> efficacy of a novel heat-activated metalloenediyne anti-cancer agent-Reference-Cited by-同舟云学术

Characterization and initial demonstration of in vivo efficacy of a novel heat-activated metalloenediyne anti-cancer agent

Published:2022-03-02 Issue:1 Volume:39 Page:405-413
ISSN:0265-6736
Container-title:International Journal of Hyperthermia
language:en
Short-container-title:International Journal of Hyperthermia

Author:

Garrett Joy¹,Metzger Erin²,Dewhirst Mark W.³,Pollok Karen E.⁴,Turchi John J.⁵,Le Poole Isabelle C.⁶,Couch Kira¹,Lew Logan¹,Sinn Anthony⁴,Zaleski Jeffrey M.²,Dynlacht Joseph R.¹

Affiliation:

1. Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis, IN, USA

2. Department of Chemistry, Indiana University, Bloomington, IN, USA

3. Department of Radiation Oncology, Duke University School of Medicine, Durham, NC, USA

4. In Vivo Therapeutics Core, Indiana University Melvin and Bren Simon Comprehensive Cancer Center, Indiana University School of Medicine, Indianapolis, IN, USA

5. Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA

6. Department of Dermatology, Northwestern University, Chicago, IL, USA

Funder

National Institutes of Health

Indiana University Melvin and Bren Simon Cancer Center Flow Cytometry Resource Facility

NIH

NIH/NCI Cancer Center Support Grant

Indiana University Simon Comprehensive Cancer Center

Publisher

Informa UK Limited

Subject

Cancer Research,Physiology (medical),Physiology

Link

https://www.tandfonline.com/doi/pdf/10.1080/02656736.2021.2024280

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1. Biosynthesis of Enediyne Antitumor Antibiotics

2. Effects of hyperthermia on DNA repair pathways: one treatment to inhibit them all

3. Hyperthermia adds to chemotherapy