Prediction of metabolic clearance using fresh human hepatocytes: Comparison with cryopreserved hepatocytes and hepatic microsomes for five benzodiazepines-Reference-Cited by-同舟云学术

Prediction of metabolic clearance using fresh human hepatocytes: Comparison with cryopreserved hepatocytes and hepatic microsomes for five benzodiazepines

Published:2008-04 Issue:4 Volume:38 Page:353-367
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Hallifax D.,Galetin A.,Houston J. B.

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

http://www.tandfonline.com/doi/pdf/10.1080/00498250701834665

Reference39 articles.

1. Time course of cytochromes P450 decline during rat hepatocyte isolation and culture: effect of l-NAME

2. Evaluation of Cryopreserved Human Hepatocytes as an Alternative in Vitro System to Microsomes for the Prediction of Metabolic Clearance

3. Effect of Quinidine on the 10-Hydroxylation ofR-Warfarin: Species Differences and Clearance Projection

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