Ketobemidone is a substrate for cytochrome P4502C9 and 3A4, but not for P-glycoprotein-Reference-Cited by-同舟云学术

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Ketobemidone is a substrate for cytochrome P4502C9 and 3A4, but not for P-glycoprotein

Published:2005-08 Issue:8 Volume:35 Page:785-796
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Yasar Ü.,Annas A.,Svensson J.-O.,Lazorova L.,Artursson P.,Al-Shurbaji A.

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

http://www.tandfonline.com/doi/pdf/10.1080/00498250500183181

Reference36 articles.

1. Al-Shurbaji, A, Säwe, J. The pharmacokinetics of ketobemidone are not affected by CYP2D6 or CYP2C19 phenotype European Journal of Clinical Pharmacology, 2002; 57: 877–881

2. Al-Shurbaji, A, Tokics, L. The pharmacokinetics of ketobemidone in critically ill patients British Journal of Clinical Pharmacology, 2002; 54: 583–586

3. Alvan, G, Bechtel, P, Iselius, L, Gundert-Remy, U. Hydroxylation polymorphisms of debrisoquine and mephenytoin in European populations European Journal of Clinical Pharmacology, 1990; 39: 533–537

4. Artursson, P. Epithelial transport of drugs in cell culture. I: A model for studying the passive diffusion of drugs over intestinal absorptive (Caco-2) cells Journal of Pharmacology Science, 1990; 79: 476–482

5. Ayrton, A, Morgan, P. Role of transport proteins in drug absorption, distribution and excretion Xenobiotica, 2001; 31: 469–497

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