Preclinical absorption, distribution, metabolism and excretion (ADME) characterization of ICAM1988, an LFA-1/ICAM antagonist, and its prodrug-Reference-Cited by-同舟云学术

Preclinical absorption, distribution, metabolism and excretion (ADME) characterization of ICAM1988, an LFA-1/ICAM antagonist, and its prodrug

Published:2008-03 Issue:3 Volume:38 Page:340-352
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Khojasteh S. C.,Leipold D. D.,Lai F.,La H.,Baumgardner M. J.,Desino K. E.,Gudmundsson O. S.,Bloedow D. C.,Bodary S. C.,Reynolds M. E.,Gadek T. R.,Kenkare-Mitra S.

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

http://www.tandfonline.com/doi/pdf/10.1080/00498250701813248

Reference12 articles.

1. Targeting ICAM-1/LFA-1 interaction for controlling autoimmune diseases: designing peptide and small molecule inhibitors

2. Design of Ester Prodrugs to Enhance Oral Absorption of Poorly Permeable Compounds: Challenges to the Discovery Scientist

3. N -Benzoyl amino acids as ICAM/LFA-1 inhibitors. Part 2: Structure–activity relationship of the benzoyl moiety

4. N-Benzoyl amino acids as LFA-1/ICAM inhibitors 1: amino acid structure–activity relationship

5. Second-Generation Lymphocyte Function-Associated Antigen-1 Inhibitors: 1H-Imidazo[1,2-α]imidazol-2-one Derivatives

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