Metabolism of the antineoplastic and immunosuppressive drug 2-CdA (Leustatin®) in animals and humans
Author:
Publisher
Informa UK Limited
Subject
Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine
Link
http://www.tandfonline.com/doi/pdf/10.1080/00498250410001713140
Reference15 articles.
1. Cladribine (2-chlorodeoxyadenosine)
2. Marrow Suppression Produced by Repeated Doses of Cladribine
3. 2-Chlorodeoxyadenosine (2-CdA): A Potent Chemotherapeutic and Immunosuppressive Nucleoside
4. Lymphospecific toxicity in adenosine deaminase deficiency and purine nucleoside phosphorylase deficiency: Possible role of nucleoside kinase(s)
5. Antileukemic and immunosuppressive activity of 2-chloro-2'-deoxyadenosine.
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1. Cladribine exerts an immunomodulatory effect on human and murine dendritic cells;International Immunopharmacology;2014-02
2. Cladribine;Handbook of Metabolic Pathways of Xenobiotics;2013-10-13
3. Comparison of thein vitroandin vivometabolism of Cladribine (Leustatin, Movectro) in animals and human;Xenobiotica;2013-04-29
4. Development and validation of an assay for the quantitative determination of cladribine nucleotides in MDCKII cells and culture medium using weak anion-exchange liquid chromatography coupled with tandem mass spectrometry;Rapid Communications in Mass Spectrometry;2007-11-15
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