In vitrometabolism of KBH-A40, a novelδ-lactam-based histone deacetylase (HDAC) inhibitor, in human liver microsomes and serum-Reference-Cited by-同舟云学术

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In vitrometabolism of KBH-A40, a novelδ-lactam-based histone deacetylase (HDAC) inhibitor, in human liver microsomes and serum

Published:2008-03 Issue:3 Volume:38 Page:281-293
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Kim H. M.,Oh S. J.,Park S.-K.,Han G.,Kim K.,Lee K. S.,Kang J. S.,Nam M.,Lee K.

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

http://www.tandfonline.com/doi/pdf/10.1080/00498250701813222

Reference25 articles.

1. Role of Histone Acetylation in the Assembly and Modulation of Chromatin Structures

2. Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer

3. Anticancer activities of histone deacetylase inhibitors

4. High turbulence liquid chromatography online extraction and tandem mass spectrometry for the simultaneous determination of suberoylanilide hydroxamic acid and its two metabolites in human serum

5. Major Phase I Biotransformation Pathways of Trichostatin A in Rat Hepatocytes and in Rat and Human Liver Microsomes

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3. Discovery of Orally Available Runt-Related Transcription Factor 3 (RUNX3) Modulators for Anticancer Chemotherapy by Epigenetic Activation and Protein Stabilization;Journal of Medicinal Chemistry;2015-04-09

4. Determination of species-difference in microsomal metabolism of amitriptyline using a predictive MRM–IDA–EPI method;Chemico-Biological Interactions;2015-03

5. Pharmacokinetics and Metabolism of 4-O -Methylhonokiol in Rats;Phytotherapy Research;2013-07-03

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