In vitromicrosomal metabolic studies on a selective mGluR5 antagonist MTEP: Characterization ofin vitrometabolites and identification of a novel thiazole ring opening aldehyde metabolite-Reference-Cited by-同舟云学术

In vitromicrosomal metabolic studies on a selective mGluR5 antagonist MTEP: Characterization ofin vitrometabolites and identification of a novel thiazole ring opening aldehyde metabolite

Published:2005-08 Issue:8 Volume:35 Page:797-809
ISSN:0049-8254
Container-title:Xenobiotica
language:en
Short-container-title:Xenobiotica

Author:

Yang X.,Chen W.

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine

Link

http://www.tandfonline.com/doi/pdf/10.1080/00498250500230412

Reference23 articles.

1. Metabotropic Glutamate Receptor mGlu5 Is a Mediator of Appetite and Energy Balance in Rats and Mice

2. Anxiolytic-like activity of the mGluR5 antagonist MPEPA comparison with diazepam and buspirone

3. Mass spectrometry of 1,2,5-oxadiazole N-oxide derivatives: use of deuterated analogues in fragmentation pattern studies

Cited by 11 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Simple In Vitro 18O Labeling for Improved Mass Spectrometry-Based Drug Metabolites Identification: Deep Drug Metabolism Study;International Journal of Molecular Sciences;2023-02-26

2. Methanol adducts leading to the identification of a reactive aldehyde metabolite of CPAQOP in human liver microsomes by ultra-high-performance liquid chromatography/mass spectrometry;Rapid Communications in Mass Spectrometry;2016-11-28

3. Comparison of trapping profiles between d -peptides and glutathione in the identification of reactive metabolites;Toxicology Reports;2015

4. d-Isomer of gly-tyr-pro-cys-pro-his-pro peptide: A novel and sensitive in vitro trapping agent to detect reactive metabolites by electrospray mass spectrometry;Toxicology in Vitro;2011-02

5. Mechanistic Studies on a P450-Mediated Rearrangement of BMS-690514: Conversion of a Pyrrolotriazine to a Hydroxypyridotriazine;Chemical Research in Toxicology;2010-11-16