Hepatotoxicity of ketoconazole in Sprague-Dawley rats: glutathione depletion, flavin-containing monooxygenases-mediated bioactivation and hepatic covalent binding
Author:
Publisher
Informa UK Limited
Subject
Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine
Link
http://www.tandfonline.com/doi/pdf/10.1080/0049825031000072243
Reference37 articles.
1. Azoles, a48 llylamines and drug metabolism
2. Pharmacokinetics of Ketoconazole Administered Intravenously to Dogs and Orally as Tablet and Solution to Humans and Dogs
3. Prolonged jaundice following ketoconazole-induced hepatic injury
4. Ketoconazole-induced fulminant hepatitis.
5. The Treatment of Advanced Prostate Cancer with Ketoconazole
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