Identification of the human cytochrome P450s responsible for thein vitrometabolism of a leukotriene B4 receptor antagonist, CP-195,543
Author:
Publisher
Informa UK Limited
Subject
Health, Toxicology and Mutagenesis,Pharmacology,Toxicology,Biochemistry,General Medicine
Link
http://www.tandfonline.com/doi/pdf/10.1080/00498250310001646362
Reference15 articles.
1. Leukocyte-endothelial adhesion molecules
2. Leukotriene B4
3. cDNA Cloning and Initial Characterization of CYP3A43, a Novel Human Cytochrome P450
4. Pharmacogenomics of cytochrome P450 and other enzymes involved in biotransformation of xenobiotics
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3. CYP2C8- and CYP3A-MediatedC-Demethylation of (3-{[(4-tert-Butylbenzyl)-(pyridine-3-sulfonyl)-amino]-methyl}-phenoxy)-acetic Acid (CP-533,536), an EP2 Receptor-Selective Prostaglandin E2 Agonist: Characterization of Metabolites by High-Resolution Liquid Chromatography-Tandem Mass Spectrometry and Liquid Chromatography/Mass Spectrometry-Nuclear Magnetic Resonance;Drug Metabolism and Disposition;2008-07-24
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