Toxic effects and molecular mechanism of doxorubicin on different organs

Toxic effects and molecular mechanism of doxorubicin on different organs – an update

Published:2021-04-21 Issue: Volume: Page:1-25
ISSN:1556-9543
Container-title:Toxin Reviews
language:en
Short-container-title:Toxin Reviews

Author:

Renu Kaviyarasi¹,Pureti Lakshmi Prasanna¹,Vellingiri Balachandar²,Valsala Gopalakrishnan Abilash¹^ORCID

Affiliation:

1. Department of Biomedical Sciences, School of Biosciences and Technology, Vellore Institute of Technology (VIT), Vellore, India

2. Human Molecular Cytogenetics and Stem Cell Laboratory, Department of Human Genetics and Molecular Biology, Bharathiar University, Coimbatore, India

Funder

VIT SEED GRANT

ICMR-National Task Force

Publisher

Informa UK Limited

Subject

Toxicology

Link

https://www.tandfonline.com/doi/pdf/10.1080/15569543.2021.1912099

Reference173 articles.

1. Effect of infliximab, a tumor necrosis factor-alpha inhibitor, on doxorubicin-induced nephrotoxicity in rats

2. The methoxychlor metabolite, HPTE, directly inhibits the catalytic activity of cholesterol side-chain cleavage (P450scc) in cultured rat ovarian cells

3. Doxorubicin-induced neurotoxicity is associated with acute alterations in synaptic plasticity, apoptosis, and lipid peroxidation

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