An assessment of compositional methods for the analysis of DNA methylation-based deconvolution estimates

Author:

Alsup Alexander1ORCID,Nissen Emily1ORCID,Salas Lucas A23ORCID,Molinaro Annette M4,Reiner Alexander5ORCID,Liu Simin6ORCID,Madsen Tracy E6,Liu Longjian7,Auer Paul L8,Christensen Brock C23ORCID,Wiencke John K4ORCID,Kelsey Karl T6ORCID,Koestler Devin C1ORCID

Affiliation:

1. Department of Biostatistics & Data Science, University of Kansas Medical Center, Kansas City, KS 66160, USA

2. Department of Epidemiology, Geisel School of Medicine, Dartmouth College, Lebanon, NH 03756, USA

3. Department of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Lebanon, NH 03756, USA

4. Department of Neurological Surgery, Institute for Human Genetics, University of California, San Francisco, San Francisco, CA 94143, USA

5. Division of Public Health Science, Fred Hutchinson Cancer Center, Seattle, WA 98109, USA

6. Department of Emergency Medicine, Alpert Medical School of Brown University and Department of Epidemiology, Department of Pathology and Laboratory Medicine, Brown University School of Public Health, Providence, RI 02903, USA

7. Department of Epidemiology and Biostatistics, Dornsife School of Public Health, Drexel University, Philadelphia, PA 19104, USA

8. Division of Biostatistics, Institute for Health & Equity, and Cancer Center, Medical College of Wisconsin, Milwaukee, WI 53226, USA

Funder

National Cancer Institute

National Institute of General Medical Sciences

Publisher

Informa UK Limited

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