DPYD and TYMS polymorphisms as predictors of 5 fluorouracil toxicity in colorectal cancer patients
Author:
Affiliation:
1. Biochemistry Department, LR12SP11, Sahloul University Hospital, Sousse, Tunisia
2. University of Monastir Faculty of Pharmacy of Monastir, Monastir, Tunisia
3. Carcinology Department, Farhat Hached University Hospital, Sousse, Tunisia
Funder
Tunisian Ministry of Higher Education, Scientific Research and Technology, and the Ministry of Health
Publisher
Informa UK Limited
Subject
Infectious Diseases,Pharmacology (medical),Pharmacology,Oncology
Link
https://www.tandfonline.com/doi/pdf/10.1080/1120009X.2022.2125736
Reference51 articles.
1. Ferlay J, Soerjomataram I, Ervik M, et al. Lyon, France: international agency for research on cancer; 2013. Cancer Incidence and Mortality Worldwide: IARC Cancer Base. 2012;(11)
2. Systemic Therapy for Colorectal Cancer
3. Importance of dihydropyrimidine dehydrogenase (DPD) deficiency in patients exhibiting toxicity following treatment with 5-fluorouracil
4. DPYD IVS14+1G>A and 2846A>T genotyping for the prediction of severe fluoropyrimidine-related toxicity: a meta-analysis
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1. MIR27A Gene Polymorphism Modifies the Effect of Common DPYD Gene Variants on Severe Toxicity in Patients with Gastrointestinal Tumors Treated with Fluoropyrimidine-Based Anticancer Therapy;International Journal of Molecular Sciences;2024-08-04
2. DPYD genetic polymorphisms in non-European patients with severe fluoropyrimidine-related toxicity: a systematic review;British Journal of Cancer;2024-06-17
3. Total neoadjuvant therapy in rectal cancer: the evidence and expectations;Critical Reviews in Oncology/Hematology;2023-12
4. Discrepancies between dihydropyrimidine dehydrogenase phenotyping and genotyping: What are the explanatory factors?;British Journal of Clinical Pharmacology;2023-03-30
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