Analytical and clinical validation of an RNA sequencing-based assay for quantitative, accurate evaluation of a molecular signature response classifier in rheumatoid arthritis
Author:
Affiliation:
1. Data Science, Scipher Medicine Corporation, Waltham, MA, USA
2. Laboratory Operations, Scipher Medicine Corporation, Waltham, MA, USA
Funder
Corporation
Publisher
Informa UK Limited
Subject
Genetics,Molecular Biology,Molecular Medicine,Pathology and Forensic Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/14737159.2021.2000394
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2. The PREMIER study: A multicenter, randomized, double-blind clinical trial of combination therapy with adalimumab plus methotrexate versus methotrexate alone or adalimumab alone in patients with early, aggressive rheumatoid arthritis who had not had previous methotrexate treatment
3. Infliximab (chimeric anti-tumour necrosis factor α monoclonal antibody) versus placebo in rheumatoid arthritis patients receiving concomitant methotrexate: a randomised phase III trial
4. Combination of infliximab and methotrexate therapy for early rheumatoid arthritis: A randomized, controlled trial
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