Establishment of a novel CYP3A4-transduced human hepatic sinusoidal endothelial cell model and its application in screening hepatotoxicity of pyrrolizidine alkaloids-Reference-Cited by-同舟云学术

Establishment of a novel CYP3A4-transduced human hepatic sinusoidal endothelial cell model and its application in screening hepatotoxicity of pyrrolizidine alkaloids

Published:2020-04-02 Issue:2 Volume:38 Page:169-185
ISSN:2689-6583
Container-title:Journal of Environmental Science and Health, Part C
language:en
Short-container-title:Journal of Environmental Science and Health, Part C

Author:

Lu Yao¹^ORCID,Wong Ka Yan¹,Tan Chunlai¹,Ma Jiang¹^ORCID,Feng Bo¹^ORCID,Lin Ge¹^ORCID

Affiliation:

1. School of Biomedical Sciences, Faculty of Medicine, the Chinese University of Hong Kong, Hong Kong SAR

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Cancer Research

Link

https://www.tandfonline.com/doi/pdf/10.1080/26896583.2020.1769409

Reference34 articles.

1. Pyrrole-protein adducts – A biomarker of pyrrolizidine alkaloid-induced hepatotoxicity

2. Pyrrolizidine Alkaloids—Genotoxicity, Metabolism Enzymes, Metabolic Activation, and Mechanisms

3. Pyrrolizidine Alkaloids: Potential Role in the Etiology of Cancers, Pulmonary Hypertension, Congenital Anomalies, and Liver Disease

4. Pyrrolizidine Alkaloids: Metabolic Activation Pathways Leading to Liver Tumor Initiation

5. Toxicity of Pyrrolizidine Alkaloids

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1. PBTK modeling of the pyrrolizidine alkaloid retrorsine to predict liver toxicity in mouse and rat;Archives of Toxicology;2023-03-11

2. Generation & characterization of expandable human liver sinusoidal endothelial cells and their application to assess hepatotoxicity in an advanced in vitro liver model;Toxicology;2023-01

3. Effects of bicyclol on hepatic sinusoidal obstruction syndrome induced by Gynura segetum;Journal of Clinical Laboratory Analysis;2022-11-29

4. Structure-Dependent Toxicokinetics of Selected Pyrrolizidine Alkaloids In Vitro;International Journal of Molecular Sciences;2022-08-16

5. A TMT-based shotgun proteomics uncovers overexpression of thrombospondin 1 as a contributor in pyrrolizidine alkaloid-induced hepatic sinusoidal obstruction syndrome;Archives of Toxicology;2022-03-31