IN VITRO HEPATIC METABOLISM OF PCBTF: DEVELOPMENT OF Vmax AND Km VALUES AND PARTITION COEFFICIENTS AND THEIR USE IN AN INHALATION PBPK MODEL

Author:

James B. Knaak,Ladd W. Smith,Richard D. Fitzpatrick,James R. Olson,Paul E. Newton

Publisher

Informa UK Limited

Subject

Health, Toxicology and Mutagenesis,Toxicology

Reference7 articles.

1. Comparison of the biotransformation of 1,3-butadiene and its metabolite, butadiene monoepoxide, by hepatic and pulmonary tissues from humans, rats and mice

2. Partition coefficients of low-molecular-weight volatile chemicals in various liquids and tissues

3. National Toxicology Program. 1991. Toxicity Studies of p-Chloro-a,a,a-Trifluorotoluene in F344/N Rats and Mice—Comparative Fourteen-Day Gavage Studies in Corn Oil and a-Cyclodextrin. March. Washington, DC: U.S. Department of Health and Human Services/NIH.

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