1. Faculty of Biology, Medicine and Health, University of Manchester, Manchester UK;
2. Gastroenterology Department, Wrightington Wigan and Leigh NHS Foundation Trust, Wigan, UK;
3. Gastroenterology Department, Salford Royal NHS Foundation Trust, Salford, UK;
4. Faculty of Biology, Medicine and Health, School of Medical Sciences, Division of Cancer Sciences, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK