1. Heart Centre, Kuopio University Hospital, Kuopio, Finland;
2. Department of Emergency, Kuopio University Hospital, Kuopio, Finland;
3. Assessment of Pharmacotherapies, Finnish Medicines Agency, Kuopio, Finland;
4. Department of Surgery, Kuopio University Hospital, Kuopio, Finland;
5. Social Insurance Institution, Regional Office for Eastern and Northern Finland, Kuopio, Finland;
6. Department of Medicine, Kuopio University Hospital, Kuopio, Finland;
7. Institute of Clinical Medicine, School of Medicine, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland