1. Department of Internal Medicine 1, J.W. Goethe University Hospital Frankfurt, Frankfurt, Germany;
2. Department of Internal Medicine 1, University Hospital Carl Gustav Carus, Dresden, Germany;
3. Department of Internal Medicine 1, University Hospital Halle (Saale), Halle, Germany;
4. Institute of Biostatistics and Math Modeling, J.W. Goethe University Hospital Frankfurt, Frankfurt, Germany