1. 1NIHR Nottingham Biomedical Research Centre, Nottingham University Hospitals NHS Trust and The University of Nottingham, Nottingham, UK;
2. 2Nottingham Digestive Diseases Centre, The University of Nottingham, Nottingham, UK;
3. 3Mayo Clinic Division of Gastroenterology and Hepatology, Rochester, MN, USA;
4. 4Department of Gastroenterology, University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK;
5. 5Sherwood Forest Hospitals NHS Foundation Trust, Kings Mill Hospital, Nottinghamshire, UK;
6. 6Department of Gastroenterology, Hellenic Red Cross Hospital, Athens, Greece;
7. 7Research Institute for Primary Care and Health Sciences, Primary Care Sciences, Keele University, Staffordshire, UK;
8. 8Department of Pathology, Nottingham University Hospitals NHS Trust, Queen's Medical Centre Campus, Nottingham, UK