Recent advances in computational metabolite structure predictions and altered metabolic pathways assessment to inform drug development processes-Reference-Cited by-同舟云学术

Recent advances in computational metabolite structure predictions and altered metabolic pathways assessment to inform drug development processes

Published:2021-05-11 Issue: Volume: Page:1-15
ISSN:0360-2532
Container-title:Drug Metabolism Reviews
language:en
Short-container-title:Drug Metabolism Reviews

Author:

Schleiff Mary Alexandra¹^ORCID,Dhaware Deepika²,Sodhi Jasleen K.³

Affiliation:

1. Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR, USA

2. Biotransformation and ADME, Research and Development, Orion Corporation, Espoo, Finland

3. Department of Bioengineering and Therapeutic Sciences, Schools of Pharmacy and Medicine, University of California San Francisco, San Francisco, CA, USA

Publisher

Informa UK Limited

Subject

Pharmacology (medical),General Pharmacology, Toxicology and Pharmaceutics

Link

https://www.tandfonline.com/doi/pdf/10.1080/03602532.2021.1910292

Reference59 articles.

1. GLORY: Generator of the Structures of Likely Cytochrome P450 Metabolites Based on Predicted Sites of Metabolism

2. BioTransformer: a comprehensive computational tool for small molecule metabolism prediction and metabolite identification

3. In Silico Absorption, Distribution, Metabolism, Excretion, and Pharmacokinetics (ADME-PK): Utility and Best Practices. An Industry Perspective from the International Consortium for Innovation through Quality in Pharmaceutical Development

4. Managing the challenge of chemically reactive metabolites in drug development

5. Investigation of toxic metabolites during drug development

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Daphnetin, a Coumarin in Genus Stellera Chamaejasme Linn: Chemistry, Bioactivity and Therapeutic Potential;Chemistry & Biodiversity;2022-08-17

2. A Comprehensive Study to Identify Major Metabolites of an Amoxicillin–Sulbactam Hybrid Molecule in Rats and Its Metabolic Pathway Using UPLC-Q-TOF-MS/MS;Metabolites;2022-07-18