1. Department of Drug Metabolism and Pharmacokinetics, Genentech Inc, South San Francisco, CA, USA;
2. Department of Medicine – Division of Clinical Pharmacology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA;
3. Department of Drug Metabolism and Pharmacokinetics, MyoKardia Inc., South San Francisco, CA, USA;
4. Department of Biochemistry and Molecular Biology, University of Arkansas for Medical Sciences, Little Rock, AR, USA;
5. Department of Safety Assessment and Laboratory Animal Resources, Merck Research Laboratories (MRL), Merck & Co., Inc, West Point, PA, USA;
6. Division of Toxicology, Wageningen University, Wageningen, The Netherlands