Efficacy of lumacaftor-ivacaftor for the treatment of cystic fibrosis patients homozygous for the F508del-CFTR mutation-Reference-Cited by-同舟云学术

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Efficacy of lumacaftor-ivacaftor for the treatment of cystic fibrosis patients homozygous for the F508del-CFTR mutation

Published:2016-04-22 Issue:3 Volume:1 Page:235-243
ISSN:2380-8993
Container-title:Expert Review of Precision Medicine and Drug Development
language:en
Short-container-title:Expert Review of Precision Medicine and Drug Development

Author:

Cholon Deborah M.,Esther Charles R.,Gentzsch Martina

Funder

Cystic Fibrosis Foundation

National Institute of Diabetes and Digestive and Kidney Diseases

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,Genetics,Molecular Medicine

Link

http://www.tandfonline.com/doi/pdf/10.1080/23808993.2016.1175299

Reference66 articles.

1. The amiloride-inhibitable Na+ conductance is reduced by the cystic fibrosis transmembrane conductance regulator in normal but not in cystic fibrosis airways.

2. Increased airway epithelial Na+ absorption produces cystic fibrosis-like lung disease in mice

3. CFTR as a cAMP-Dependent Regulator of Sodium Channels

4. A new role for bicarbonate in mucus formation

5. Native Small Airways Secrete Bicarbonate

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1. Impact of lumacaftor/ivacaftor on nutrition and growth in modulator-naïve children over 24 weeks;Journal of Cystic Fibrosis;2024-07

2. Impaired intestinal free fatty acid transport followed by chylomicron malformation, not pancreatic insufficiency, cause metabolic defects in cystic fibrosis;Journal of Lipid Research;2024-07

3. A reproduced combination of ivacaftor and lumacaftor, CFTR protein modulators. Ethical and pharmacokinetic aspects;Медицинская этика;2024-06

4. Drug Optimization for Cystic Fibrosis Patients Based on Disease Pathways Crosstalk;Research Anthology on Bioinformatics, Genomics, and Computational Biology;2023-12-29

5. Pyronaridine as a Bromodomain-Containing Protein 4-N-Terminal Bromodomain (BRD4-BD1) Inhibitor: In Silico Database Mining, Molecular Docking, and Molecular Dynamics Simulation;Molecules;2023-07-28

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