1. Team Biostatistics and Big Medical Data, IDA Lab Salzburg, Paracelsus Medical University, Salzburg, Austria;
2. Department of Mathematics, Paris-Lodron-University of Salzburg, Salzburg, Austria;
3. Department of Research and Innovation, Paracelsus Medical University, Salzburg, Austria;
4. Department of Medical Statistics, University of Göttingen, Göttingen, Germany;
5. Competence Centre for Clinical Trials, University of Bremen, Bremen, Germany;
6. Team Smart Analytics, IDA Lab Salzburg, Paris-Lodron-University of Salzburg, Salzburg, Austria