The ‘in vivo lifestyle’ of bile acid 7α-dehydroxylating bacteria: comparative genomics, metatranscriptomic, and bile acid metabolomics analysis of a defined microbial community in gnotobiotic mice

Author:

Ridlon Jason M.12345,Devendran Saravanan12,Alves João Mp6,Doden Heidi12,Wolf Patricia G.123ORCID,Pereira Gabriel V.12ORCID,Ly Lindsey13,Volland Alyssa12,Takei Hajime7,Nittono Hiroshi7,Murai Tsuyoshi8,Kurosawa Takao8,Chlipala George E.9,Green Stefan J.9,Hernandez Alvaro G.10ORCID,Fields Christopher J.10,Wright Christy L.10ORCID,Kakiyama Genta11,Cann Isaac1231012,Kashyap Purna1314,McCracken Vance1315,Gaskins H. Rex234

Affiliation:

1. Microbiome Metabolic Engineering Theme, Carl R. Woese Institute for Genomic Biology, Urbana, IL, USA

2. Department of Animal Sciences, University of Illinois at Urbana-Champaign, Urbana, IL, USA

3. Division of Nutritional Sciences, University of Illinois at Urbana-Champaign, Urbana, IL, USA

4. Cancer Center at Illinois, University of Illinois at Urbana-Champaign, Urbana, IL, USA

5. Department of Microbiology and Immunology, School of Medicine, Virginia Commonwealth University, Richmond, VA, USA

6. Department of Parasitology, Institute of Biomedical Sciences, University of São Paulo, São Paulo, Brazil

7. Junshin Clinic Bile Acid Institute, Meguro-Ku, Tokyo, Japan

8. School of Pharmaceutical Sciences, Health Sciences University of Hokkaido, Ishikari-Tobetsu, Hokkaido, Japan

9. UIC Research Resources Center, University of Illinois at Chicago, Chicago, IL, USA

10. Keck Center for Biotechnology, University of Illinois at Urbana-Champaign, Urbana, IL, USA

11. Department of Internal Medicine, School of Medicine, Virginia Commonwealth University, Richmond, VA, USA

12. Department of Microbiology, University of Illinois at Urbana-Champaign, Urbana, IL, USA

13. Department of Physiology & Biomedical Engineering, Mayo Clinic, Rochester, MN, USA

14. Division of Gastroenterology and Hepatology, Department of Internal Medicine, Mayo Clinic, Rochester, MN, USA

15. Department of Biological Sciences, Southern Illinois University Edwardsville, Edwardsville, IL, USA

Funder

College of Agricultural, Consumer and Environmental Sciences, University of Illinois at Urbana-Champaign

National Cancer Institute

National Institute of Food and Agriculture

Publisher

Informa UK Limited

Subject

Infectious Diseases,Microbiology (medical),Gastroenterology,Microbiology

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