The propionate-GPR41 axis in infancy protects from subsequent bronchial asthma onset

Author:

Ito Takashi1,Nakanishi Yumiko1,Shibata Ryohei12,Sato Noriko13,Jinnohara Toshi1,Suzuki Sayo1,Suda Wataru4,Hattori Masahira4,Kimura Ikuo56,Nakano Taiji3,Yamaide Fumiya3,Shimojo Naoki37,Ohno Hiroshi1489ORCID

Affiliation:

1. Laboratory for Intestinal Ecosystem, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan

2. Department of Pediatric Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan

3. Department of Pediatrics, Graduate School of Medicine, Chiba University, Chiba, Japan

4. Laboratory for Microbiome Sciences, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan

5. Department of Signal Transductions, Graduate School of Biostudies, Kyoto University, Kyoto, Japan

6. Department of Applied Biological Science, Graduate School of Agriculture, Tokyo University of Agriculture and Technology, Tokyo, Japan

7. Center for Preventive Medical Sciences, Chiba University, Chiba, Japan

8. Laboratory for Immune Regulation, Graduate School of Medical and Pharmaceutical Sciences, Chiba University, Chiba, Japan

9. Immunobiology Laboratory, Department of Medical Life Science, Graduate School of Medical Life Science, Yokohama City University, Yokohama, Japan

Funder

This work was supported in part by

grant from

Japan Society for the Promotion of Science at https://www.jsps.go.jp/english/e-grants/: Grants-in-Aid for Young Scientists

The Japan Agency for Medical Research and Development at https://www.amed.go.jp/en/index.html: AMED

The Japan Agency for Medical Research and Development at https://www.amed.go.jp/en/index.html: AMED-CREST

Publisher

Informa UK Limited

Subject

Infectious Diseases,Microbiology (medical),Gastroenterology,Microbiology

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