A compromised developmental trajectory of the infant gut microbiome and metabolome in atopic eczema

Author:

Ta Le Duc Huy1,Chan James Chun Yip23ORCID,Yap Gaik Chin1,Purbojati Rikky W.4ORCID,Drautz-Moses Daniela I.4ORCID,Koh Yanqing Michelle4,Tay Carina Jing Xuan1,Huang Chiung-Hui1,Kioh Dorinda Yan Qin5,Woon Jia Yun5,Tham Elizabeth Huiwen16ORCID,Loo Evelyn Xiu Ling7,Shek Lynette P.C.16,Karnani Neerja7,Goh Anne8,Van Bever Hugo P.S.16,Teoh Oon Hoe8ORCID,Chan Yiong Huak9,Lay Christophe110,Knol Jan1112,Yap Fabian8,Tan Kok Hian8,Chong Yap-Seng713,Godfrey Keith M.14,Kjelleberg Staffan4,Schuster Stephan C.4,Chan Eric Chun Yong357,Lee Bee Wah1

Affiliation:

1. Department of Paediatrics, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

2. Skin Research Institute of Singapore, A*STAR, Singapore

3. Innovations in Food & Chemical Safety Programme, A*STAR

4. Singapore Centre For Environmental Life Sciences Engineering (SCELSE), Nanyang Technological University, Singapore

5. Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore

6. Khoo Teck Puat-National University Children’s Medical Institute, National University Health System, Singapore

7. Singapore Institute for Clinical Sciences (SICS), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore

8. Department of Paediatrics, KK Women’s and Children’s Hospital, Singapore

9. Biostatistics Unit, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore

10. Danone Nutricia Research, Singapore

11. Danone Nutricia Research, Utrecht, The Netherlands

12. Laboratory of Microbiology, Wageningen University, Wageningen, The Netherlands

13. Department of Obstetrics & Gynaecology, National University of Singapore, Singapore

14. MRC Lifecourse Epidemiology Unit and NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, UK

Funder

Singapore Ministry of Health National Medical Research Council

Publisher

Informa UK Limited

Subject

Infectious Diseases,Microbiology (medical),Gastroenterology,Microbiology

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