Maternal smoking during pregnancy increases the risk of gut microbiome-associated childhood overweight and obesity

Author:

Peng Ye123ORCID,Tun Hein M123ORCID,Ng Siew C234,Wai Hogan Kok-Fung5,Zhang Xi13,Parks Jaclyn67,Field Catherine J8,Mandhane Piush9,Moraes Theo J10,Simons Elinor11,Turvey Stuart E12,Subbarao Padmaja10,Brook Jeffrey R13,Takaro Tim K6,Scott James A13,Chan Francis KL23,Kozyrskyj Anita L9ORCID

Affiliation:

1. The Jockey Club School of Public Health and Primary Care, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, SAR, China

2. Microbiota I-Center (MagIC), Hong Kong, SAR, China

3. Li Ka Shing Institute of Health Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, SAR, China

4. Department of Medicine and Therapeutics, Institute of Digestive Disease, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, SAR, China

5. HKU-Pasteur Research Pole, School of Public Health, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, SAR, China

6. Faculty of Health Sciences, Simon Fraser University, Burnaby, BC, Canada

7. Cancer Control Research, BC Cancer Research Institute, Vancouver, BC, Canada

8. Department of Agricultural, Food & Nutritional Science, University of Alberta, Edmonton, AB, Canada

9. Department of Pediatrics, University of Alberta, Edmonton, AB, Canada

10. Department of Pediatrics, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada

11. Department of Pediatrics and Child Health, Children’s Hospital Research Institute of Manitoba, University of Manitoba, Winnipeg, Canada

12. Department of Pediatrics, Child and Family Research Institute, BC Children’s Hospital, University of British Columbia, Vancouver, BC, Canada

13. Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada

Funder

Chinese University of Hong Kong

Research Grants Council

Canadian Institutes of Health Research Canadian Microbiome Initiative

Canadian Institutes of Health Research and the Allergy, Genes, and Environment (AllerGen) Network of Centres of Excellence

anadian Healthy Infant Longitudinal Development (CHILD) Study

Research Committee Postdoctoral Fellowship Scheme of the Chinese University of Hong Kong

InnoHK, the Government of Hong Kong, Special Administrative Region of the People’s Republic of China

Publisher

Informa UK Limited

Reference60 articles.

1. World Health Organization. Fact sheets on obesity and overweight available from https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight#:~:text=Key%20facts has%20nearly%20tripled%20since%201975.&text=39%20million%20children%20under%20the overweight%20or%20obese%20in%202016.

2. Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults

3. World Health Organization. Taking action on childhood obesity (2018). https://apps.who.int/iris/handle/10665/274792.

4. Obesity: Epidemiology, Pathophysiology, and Therapeutics

5. The Epidemiology of Obesity: A Big Picture

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