Synthesis and <i>in Silico</i> Antiviral Activity of Novel Bioactive Thiobarbituric Acid Based Hydrazones and Pyrazoles against SARS-CoV-2 Main Protease (Mpro)-Reference-Cited by-同舟云学术

Synthesis and in Silico Antiviral Activity of Novel Bioactive Thiobarbituric Acid Based Hydrazones and Pyrazoles against SARS-CoV-2 Main Protease (Mpro)

Published:2022-10-28 Issue: Volume: Page:1-16
ISSN:1040-6638
Container-title:Polycyclic Aromatic Compounds
language:en
Short-container-title:Polycyclic Aromatic Compounds

Author:

Abolibda Tariq Z.¹,Fathalla Maher¹²,Aljohani Ghadah F.³,Zayed Ehab M.⁴,Gomha Sobhi M.⁵^ORCID

Affiliation:

1. Chemistry Department, Faculty of Science, Islamic University of Madinah, Madinah, Saudi Arabia

2. Department of Chemistry, Faculty of Science, Zagazig University, Zagazig, Egypt

3. Chemistry Department, College of Science, Taibah University, Al-Madinah Al Munawarah, Saudi Arabia

4. Department of Green Chemistry, National Research Centre, Dokki, Giza, Egypt

5. Department of Chemistry, Faculty of Science, Cairo University, Cairo, Egypt

Publisher

Informa UK Limited

Subject

Materials Chemistry,Organic Chemistry,Polymers and Plastics

Link

https://www.tandfonline.com/doi/pdf/10.1080/10406638.2022.2138922

Reference53 articles.

1. World Health Organization, Coronavirus Disease 2019 (COVID-19): Situation Report 72 (2020)

2. Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors

3. Significance and Biological Importance of Pyrimidine in the Microbial World

4. Synthesis and QSAR studies of pyrimido[4,5-d]pyrimidine-2,5-dione derivatives as potential antimicrobial agents

5. S. Ito, K. Masuda, S. Kusano, T.Nagata, Y.Kojima, N. Sawai, S.I. Maeno. “Pyrimidine Derivative, Process for Preparing Same and Agricultural or Horticultural Fungicidal Composition Containing Same” (US Patent 4, 988, 704, 1991).

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