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A Computational Study on the Structural Prediction of InhA Inhibitors as Antimycobacterial Agents

  • Published:2023-09-25 Issue: Volume: Page:1-21
  • ISSN:1040-6638
  • Container-title:Polycyclic Aromatic Compounds
  • language:en
  • Short-container-title:Polycyclic Aromatic Compounds

Author:

Wahan Simranpreet K.1,Pathania Shelly2,Chawla Pooja A.3ORCID,Bhargava Gaurav1

Affiliation:

1. Department of Chemical Sciences, IK Gujral Punjab Technical University, Kapurthala, Punjab, India

2. Integrative Physiology and Pharmacology, Institute of Biomedicine, Faculty of Medicine, University of Turku, Turku, Finland

3. Department of Pharmaceutical Chemistry, ISF College of Pharmacy, Moga, Punjab, India

Funder

DST INSPIRE

Publisher

Informa UK Limited

Subject

Materials Chemistry,Organic Chemistry,Polymers and Plastics

Reference23 articles.

1. Impact of the COVID-19 Pandemic on TB Detection and Mortality in 2020. Geneva: World Health Organization, 2021.

2. Tuberculosis Data: Provisional TB Notifications by Month or Quarter, Geneva: World Health Organization, 2021.

3. InhA, a target of the antituberculous drug isoniazid, is involved in a mycobacterial fatty acid elongation system, FAS-II

4. Modification of the NADH of the Isoniazid Target (InhA) from Mycobacterium tuberculosis

5. Mechanisms of action of isoniazid

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