Investigation of the Anti-Plasmodial Properties of N-2-Oxo Pyrrolidine Pentanamide-Based Sulfonamides: Experimental and Theoretical Approach

Author:

Asogwa Fredrick C.1,C. Ekoh Ogechi2,I. Ugwu David3,Agwamba Ernest C.4,Louis Hitler15,U. Eze Florence3,Benjamin Innocent1,Ejiofor Emmanuel U.4,Matthias Gideon E.1,A. Ezugwu James3,Owen Aniekan E.6,Okoro Uchechukwu C.3

Affiliation:

1. Computational and Bio-Simulation Research Group, Department of Pure and Applied Chemistry, University of Calabar, Calabar, Cross River State, Nigeria

2. Department of industrial Chemistry, Evangel University, Akaeze, Ebonyi State, Nigeria

3. Department of Pure & Industrial Chemistry, University of Nigeria, Nsukka, Enugu State, Nigeria

4. Department of Chemical Sciences, Clifford University, Owerrinta, Nigeria

5. Faculty of Allied Health Sciences, Chettinad Hospital and Research Institute, Chettinad Academy or Research and Education, Kelambakkam, Tamil Nadu 603103, India

6. Department of Chemistry, Akwa Ibom State University, Uyo, Akwa Ibom State

Publisher

Informa UK Limited

Subject

Materials Chemistry,Organic Chemistry,Polymers and Plastics

Reference58 articles.

1. N. Dharani, G. Rukunga, A. YenesewMbora, A. Mbora, L. Mwaura, I. Dawson, and R. Jamnadass, Common Antimalarial Trees and Shrubs of East Africa: A Description of Species and a Guide to Cultivation and Conservation through Use, Dawson I e.; The World Agroforestry Centre (ICRAF): Nairobi, Kenya, 2010.

2. World Health Organization (WHO). Malaria https://www.who.int/news-room/fact-sheets/detail/malaria (accessed Aug 7, 2022).

3. Antimalarial potential of naphthalene-sulfonic acid derivatives: Molecular electronic properties, vibrational assignments, and in-silico molecular docking studies

4. Malaria in the Pregnant Traveler

5. Structural Basis for Bisphosphonate-mediated Inhibition of Isoprenoid Biosynthesis

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