Therapeutic applications of the versatile fatty acid mimetic WY14643
Author:
Affiliation:
1. Institute of Pharmaceutical Chemistry, Goethe University Frankfurt, Frankfurt, Germany
Publisher
Informa UK Limited
Subject
Drug Discovery,Pharmacology,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/13543776.2017.1272578
Reference51 articles.
1. A potent antihypercholesterolemic agent: [4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio]acetic acid (Wy-14643)
2. Fatty acids activate a chimera of the clofibric acid-activated receptor and the glucocorticoid receptor.
3. Pirinixic acids: flexible fatty acid mimetics with various biological activities
4. Effect of wy-14,643 on cholesterol metabolism in normal and hypercholesterolemic rats
5. Statins and PPARα agonists induce myotoxicity in differentiated rat skeletal muscle cultures but do not exhibit synergy with co-treatment
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