Progress in acetylcholinesterase reactivators and in the treatment of organophosphorus intoxication: a patent review (2006

Progress in acetylcholinesterase reactivators and in the treatment of organophosphorus intoxication: a patent review (2006–2016)

Published:2017-06-06 Issue:9 Volume:27 Page:971-985
ISSN:1354-3776
Container-title:Expert Opinion on Therapeutic Patents
language:en
Short-container-title:Expert Opinion on Therapeutic Patents

Author:

Gorecki Lukas¹²,Korabecny Jan¹²,Musilek Kamil²³,Nepovimova Eugenie¹²,Malinak David²⁴,Kucera Tomas¹,Dolezal Rafael²³,Jun Daniel¹²,Soukup Ondrej¹²,Kuca Kamil²³

Affiliation:

1. Department of Toxicology and Military Pharmacy, Faculty of Military Health Sciences, University of Defence, Hradec Kralove, Czech Republic

2. Biomedical Research Centre, University Hospital Hradec Kralove, Hradec Kralove, Czech Republic

3. Faculty of Science, Department of Chemistry, University of Hradec Kralove, Hradec Kralove, Czech Republic

4. Department of Physiology and Pathophysiology, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic

Publisher

Informa UK Limited

Subject

Drug Discovery,Pharmacology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/13543776.2017.1338275

Reference63 articles.

1. Acetylcholinesterase: Mechanism of Catalysis and Inhibition

2. Acetylcholinesterase: Molecular Modeling with the Whole Toolkit

3. Review of human butyrylcholinesterase structure, function, genetic variants, history of use in the clinic, and potential therapeutic uses

4. Learning performances and vulnerability to amyloid toxicity in the butyrylcholinesterase knockout mouse

5. The Peripheral Anionic Site of Acetylcholinesterase: Structure, Functions and Potential Role in Rational Drug Design

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