Aldo-Keto Reductase (AKR) 1C3 inhibitors: a patent review
Author:
Affiliation:
1. Center of Excellence in Environmental Toxicology & Department of Systems Pharmacology & Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA
Funder
National Institutes of Health
Publisher
Informa UK Limited
Subject
Drug Discovery,Pharmacology,General Medicine
Link
https://www.tandfonline.com/doi/pdf/10.1080/13543776.2017.1379503
Reference74 articles.
1. Aldo-Keto Reductases and Bioactivation/Detoxication
2. Human aldo–keto reductases: Function, gene regulation, and single nucleotide polymorphisms
3. Overexpression of aldo-keto reductase 1C3 (AKR1C3) in LNCaP cells diverts androgen metabolism towards testosterone resulting in resistance to the 5α-reductase inhibitor finasteride
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