The inositol-1,2-cyclic phosphate moiety of the cross-reacting determinant, carbohydrate chains, and proteinaceous components are all responsible for the cross-reactivity of trypanosome variant surface glycoproteins
Author:
Affiliation:
1. Departamento de Biología Celular, Universidad Simón Bolívar, Caracas, Venezuela
2. Facultad de Ciencias Naturales y Ambientales, Universidad Internacional SEK, Quito, Ecuador
Funder
Fondo Nacional de Ciencia Tecnología e Innovación
Decanato de Investigación y Desarrollo, Universidad Simón Bolívar
Publisher
Informa UK Limited
Subject
Medical Laboratory Technology,Clinical Biochemistry,Immunology,Immunology and Allergy
Link
https://www.tandfonline.com/doi/pdf/10.1080/15321819.2017.1414701
Reference20 articles.
1. How Does the VSG Coat of Bloodstream Form African Trypanosomes Interact with External Proteins?
2. Specializations in a successful parasite: What makes the bloodstream-form African trypanosome so deadly?
3. Masters of Disguise: Antigenic Variation and the VSG Coat in Trypanosoma brucei
4. Evaluation of variant specific trypanolysis tests for serodiagnosis of human infections with Trypanosoma brucei gambiense
5. Trypanosoma evansi: Cloning and Expression in Spodoptera fugiperda Insect Cells of the Diagnostic Antigen RoTat1.2
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1. Reversible phosphorylation of a protein from Trypanosoma equiperdum that exhibits homology with the regulatory subunits of mammalian cAMP-dependent protein kinases;Biochimie;2021-02
2. Dominant IgM synthesis against the soluble form of the prevailing variant surface glycoprotein from TeAp-N/D1 Trypanosoma equiperdum throughout the experimental acute infections of horses with non-tsetse transmitted Trypanozoon parasites;Journal of Immunoassay and Immunochemistry;2020-06-11
3. High immunological response against a Trypanosoma equiperdum protein that exhibits homology with the regulatory subunits of mammalian cAMP-dependent protein kinases;Journal of Immunoassay and Immunochemistry;2018-07-04
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