Inactivation of the riboswitch-controlled GMP synthase GuaA in Clostridioides difficile is associated with severe growth defects and poor infectivity in a mouse model of infection
Author:
Affiliation:
1. Department of Microbiology and Infectious Diseases, Faculty of Medicine and Health Sciences, Université De Sherbrooke, Sherbrooke, Quebec, Canada
2. Department of Biology, Faculty of Science, Université De Sherbrooke, Sherbrooke, Quebec, Canada
Funder
National Institutes of Health
Publisher
Informa UK Limited
Subject
Cell Biology,Molecular Biology
Link
https://www.tandfonline.com/doi/pdf/10.1080/15476286.2021.1978768
Reference41 articles.
1. Clostridioides difficile: diagnosis and treatments
2. Update on Treatment of Clostridioides difficile Infection
3. Cost-effectiveness of Treatment Regimens for Clostridioides difficile Infection: An Evaluation of the 2018 Infectious Diseases Society of America Guidelines
4. The promise of riboswitches as potential antibacterial drug targets
5. Riboswitches as antibacterial drug targets
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