The voltage-gated K+ channel Kv1.3 modulates platelet motility and α2β1 integrin-dependent adhesion to collagen-Reference-Cited by-同舟云学术

The voltage-gated K+ channel Kv1.3 modulates platelet motility and α2β1 integrin-dependent adhesion to collagen

Published:2021-08-04 Issue: Volume: Page:1-11
ISSN:0953-7104
Container-title:Platelets
language:en
Short-container-title:Platelets

Author:

Wright Joy R¹²,Jones Sarah²³,Parvathy Sasikumar⁴,Kaczmarek Leonard K⁵,Forsythe Ian⁶,Farndale Richard W⁷,Gibbins Jonathan M⁴^ORCID,Mahaut-Smith Martyn P²

Affiliation:

1. Department of Cardiovascular Sciences, University of Leicester, Leicester, UK

2. Department of Molecular and Cell Biology, University of Leicester, Leicester, UK

3. Department of Life Sciences, Manchester Metropolitan University, Manchester, UK

4. Institute for Cardiovascular and Metabolic Research, University of Reading, Reading, UK

5. Department of Cellular and Molecular Physiology, Yale University School of Medicine, USA

6. Department of Neuroscience, Psychology and Behaviour, University of Leicester, Leicester, UK

7. Department of Biochemistry, University of Cambridge, Cambridge, UK

Funder

British Heart Foundation

Publisher

Informa UK Limited

Subject

Hematology,General Medicine

Link

https://www.tandfonline.com/doi/pdf/10.1080/09537104.2021.1942818

Reference72 articles.

1. Kv1.3 Channel Gene-Targeted Deletion Produces “Super-Smeller Mice” with Altered Glomeruli, Interacting Scaffolding Proteins, and Biophysics

2. The voltage-gated potassium channel Kv1.3 regulates peripheral insulin sensitivity

3. The functional network of ion channels in T lymphocytes

4. Selective Kv1.3 channel blocker as therapeutic for obesity and insulin resistance

5. Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases

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