Amplification of lmbB1 gene in Streptomyces lincolnensis improves quantity and quality of lincomycin A fermentation
Author:
Affiliation:
1. The State Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China;
2. Topfond Pharmaceutical Co., Ltd, Henan, China
Publisher
Informa UK Limited
Subject
General Medicine,Biochemistry,Biotechnology
Link
https://www.tandfonline.com/doi/pdf/10.1080/10826068.2019.1710714
Reference33 articles.
1. Biosynthesis of the lincomycins. 1. Studies using stable isotopes on the biosynthesis of the propyl- and ethyl-L-hygric acid moieties of lincomycins A and B
2. Metabolic coupling of two small-molecule thiols programs the biosynthesis of lincomycin A
3. Lincomycin, clindamycin and their applications
4. Improved industrial fermentation of lincomycin by phosphorus feeding
5. Chemical Studies on Lincomycin. I. The Structure of Lincomycin
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1. Effects of the pleiotropic regulator DasR on lincomycin production in Streptomyces lincolnensis;Applied Microbiology and Biotechnology;2024-06-15
2. Analysis of Secondary Metabolite Synthesis Potential of Streptomyces fradiae sf106 Based on the Whole Genome and Non-Target Metabolomics and Exploration of the Biosynthesis of Tylosin;Fermentation;2023-09-25
3. Simultaneous improvement of lincomycin A production and reduction of lincomycin B levels in Streptomyces lincolnensis using a combined medium optimization approach;Annals of Microbiology;2022-04-04
4. Rational engineering strategies for achieving high-yield, high-quality and high-stability of natural product production in actinomycetes;Metabolic Engineering;2021-09
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